If you have any of these, do not wait it out. Call 911 or go to an ER. Call 988 for the suicide and crisis lifeline. Withdrawal seizures and delirium tremens are fatal — never quit heavy drinking cold-turkey without medical help.
Brain
Organ Failure Including Death — Go to a Hospital.
Severe Headaches
Repeated Vomiting
Slurred Speech
Worsening Confusion
Unequal Pupil Sizes
Returning Symptoms After They Had Settled
Suicidal Ideation
Liver
Organ Failure — Go to a Hospital.
Yellow Eyes or Skin
Vomiting Blood
Black Tarry Stools
Swollen Hard Abdomen
Confusion or Drowsiness
Heart
Organ Failure — Go to a Hospital.
Crushing or Radiating Chest Pain
Fainting
Severe Breathlessness at Rest
Coughing Pink Frothy Sputum
Nerves
Organ Failure — Go to a Hospital.
Rapidly Spreading Weakness
Loss of Bladder or Bowel Control
Sudden Inability to Lift the Foot
Stomach & Digestion
Organ Failure — Go to a Hospital.
Vomiting Blood or Coffee Grounds
Black Tarry Stools
Severe Unrelenting Abdominal Pain
Unable to Keep Fluids Down
Pancreas
Organ Failure — Go to a Hospital.
Severe Constant Abdominal Pain
Fever with Abdominal Pain
Persistent Vomiting
Racing Pulse with Abdominal Pain
Skin
Organ Failure — Go to a Hospital.
Yellowing of the Skin or Eyes
Spreading Red Painful Swelling
Blood
Organ Failure — Go to a Hospital.
Bleeding That Will Not Stop
Blood in Urine or Stool
Extreme Weakness with a Racing Heart
Fever with Shaking Chills
Bones
Organ Failure — Go to a Hospital.
Sudden Severe Back Pain
Deep Groin or Hip Pain When Weight-Bearing
Inability to Bear Weight After a Fall
Cancer Warning Signs
Organ Failure — Go to a Hospital.
A Lump in the Neck or Throat
Difficulty or Pain Swallowing
Hoarseness Lasting Weeks
A Mouth Sore That Will Not Heal
Coughing Up Blood
Blood in the Stool
Unexplained Weight Loss
A New Breast Lump
Persistent Indigestion
A Change in Bowel Habit Lasting Weeks
This list is not the full picture — it is only the symptoms urgent enough to act on immediately. For everything else damage causes along the way, and what tends to heal versus what tends to stay, see the full Organ Damage page.